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three, so it had been not likely that there was multicollinearity within the various linear regression types. In addition, we executed sensitivity analyses by utilizing urinary creatinine focus (log-transformed) for a covariate as opposed to creatinine-altered urinary hefty steel concentrations and together with interaction phrases concerning both harmful major metals (As, Cd, and Pb) or Se; Not one of the urinary creatinine focus and the conversation conditions was statistically significant, and General associations among urinary major metals and hypertension did not modify (Tables S1 and S2).

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聖マリアンナ医科大学心臓血管外科 准教授。医師。医学博士。心臓外科医として東京大学医学部附属病院や聖マリアンナ医科大学病院で多数の心臓病、循環器病患者の治療に携わっている。東京大学医学部卒業。 監査役　馬越 洋介

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We found that urinary Pb concentration was positively linked to SBP and DBP in people of 4 Asian countries. Notably, this association was present inside the context of lower urinary Pb concentrations, supporting the toxicity of Pb with regard to hypertension among the populations in non-contaminated areas.